By Eric S. Weiss, William A. Baumgartner (auth.), Robert S. Bonser, Domenico Pagano, Axel Haverich (eds.)
Brain damage is still probably the most dreaded issues of cardiac surgical procedure. the diversity of harm is vast; whereas a stroke could be simply outlined and clinically determined, extra refined accidents most certainly ensue. There is still debate as to how those are clinically determined and there's a loss of typical definitions permitting inter-study comparability. If we're to have faith in ideas that can decrease mind damage, we have to trust within the end-points used to outline that harm. we have to higher comprehend the phenomena linked to neuropsychometric checking out; we have to absolutely elucidate the connection among structural mind harm, embolism counting, and surrogate biomarkers; and we want a higher realizing of the scientific value of abnormalities detected on postoperative magnetic resonance imaging. mind defense in Cardiac surgical procedure offers an in depth history of reviews of neurological morbidity and neuroprotection from quite a number specialists within the box of neuroprotection, supplying a close reference for clinicians within the box. The Editors have exact connections among the several strands of damage — be it the pathology, the imaging, the medical and cognitive exam, power biomarkers — and feature then supplied precis stories of therapy concepts that can decrease such damage. As we glance to the long run, the layout of reviews trying to lessen such harm turns into more and more vital and this e-book offers the elemental heritage details to gas curiosity, start up novel prevention and healing thoughts, and tell the investigator find out how to enhance and layout their study study.
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Additional resources for Brain Protection in Cardiac Surgery: Volume 1
Evaluation of brain injury after coronary artery bypass grafting. A prospective study using neuropsychological assessment and diffusionweighted magnetic resonance imaging. Eur J Cardiothorac Surg. 2004;25(5):791-800. Barber PA, Hach S, Tippett LJ, Ross L, Merry AF, Milsom P. Cerebral ischemic lesions on diffusion-weighted imaging are associated with neurocognitive decline after cardiac surgery. Stroke 2008 March 6. Wityk RJ, Goldsborough MA, Hillis A, et al. Diffusion- and perfusion-weighted brain magnetic resonance imaging in patients with neurologic complications after cardiac surgery.
Effect of aortic cannula characteristics and blood velocity on transcranial doppler-detected microemboli during cardiopulmonary bypass. J Cardiothorac Vasc Anesth. 1998;12:266-269. Banbury MK, Kouchoukos NT, Allen KB, et al. Emboli capture using the Embol-X intraaortic filter in cardiac surgery: a multicentered randomized trial of 1, 289 patients. Ann Thorac Surg. 2003;76:508-515. Reichenspurner H, Navia JA, Berry G, et al. Particulate emboli capture by an intra-aortic filter device during cardiac surgery.
Stroke 2008 March 6. Wityk RJ, Goldsborough MA, Hillis A, et al. Diffusion- and perfusion-weighted brain magnetic resonance imaging in patients with neurologic complications after cardiac surgery. Arch Neurol. 2001;58(4):571-576. Cook DJ, Huston J III, Trenerry MR, Brown RD Jr, Zehr KJ, Sundt TM III. Postcardiac surgical cognitive impairment in the aged using diffusion-weighted magnetic resonance imaging. Ann Thorac Surg. 2007;83(4):1389-1395. Taggart DP, Westaby S. Neurological and cognitive disorders after coronary artery bypass grafting.