By Association of Nurses in AIDS Care (ANAC)
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Extra resources for ANAC's Core Curriculum for HIV AIDS in Nursing, Third Edition
The HIV-1 pandemic today comprises multiple epidemics that differ in scale, timing, and etiologic determinants. i) HIV-1 distribution is characterized by a marked heterogeneity across continents. ii) Even within single countries, there are mixed low- and high-prevalence populations. iii) WHO and UNAIDS identify three types of HIV epidemics for HIV planning purposes, and a fourth has been proposed: (1) Low-level: Despite its presence for many years, largely confined to groups with higher risk behaviors, HIV incidence has never reached significant levels in any subpopulation.
Qxd:ANAC 26 CHAPTER 1 6/12/09 7:34 AM Page 26 HIV INFECTION, TRANSMISSION, AND PREVENTION to have occurred as the result of hunting and dressing of infected chimpanzees and sooty mangabeys. 3. Normal immunology (Medzhitov, 2007) a. Cells of the immune system i) Types of leukocytes (white blood cells) (1) Neutrophils: Major phagocytic cells in the blood. They represent approximately 60% of circulating leukocytes. Production is regulated by inflammatory cytokines: GCSF and GMCSF. (2) Eosinophils: Participate in allergic reactions.
Liaisons, hookups) and anonymous partnering (i) Know one’s own and partner’s status. , increase both susceptibility and infectiousness). (b) Alterations of normal mucosal barriers, such as genital ulcers or other lesions (due to trauma or disease) on either the infected person or the uninfected exposed person may increase the risks of transmission. (c) Mechanical contraceptive barriers may traumatize the vagina or alter the integrity of the uterine cervix. (d) The spermicide Nonoxynol-9 enhances transmission (despite previous recommendations for its use to inhibit transmission).