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By ICM-1966, Moscow.

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Only 25–30% of patients with N0 neck are found to have metastatic neck nodes at surgery. This means that the majority of patients with N0 neck undergoing a potentially morbid neck dissection are unlikely to benefit from this procedure. In three studies totaling 48 patients, where a sentinel node biopsy with immunohistochemistry was used as the gold standard, the detection rate of PET for nodal involvement in clinically N0 patients was limited between 0 and 30% (13–15). Integrated PET-CT may improve the accuracy in clinically N0 neck, with a reported sensitivity and specificity of 67 and 85%; however, this is still not sufficient to replace surgical staging in these patients (16).

2008) A systematic review and meta-analysis of the role of positron emission tomography in the follow up of head and neck squamous cell carcinoma following radiotherapy or chemoradiotherapy. Clin Otolaryngol 33, 210–22. , et al. (2009) Clinical significance of postradiotherapy [18 F]-fluorodeoxyglucose positron emission tomography imaging in management of head-and-neck cancer – a long-term outcome report. Int J Radiat Oncol Biol Phys 74, 9–14. , et al. (2001) Serial positron emission tomography scans following radiation therapy of patients with head and neck cancer.

Dulguerov, P. (2004) Prediction of outcome in head-andneck cancer patients using the standardized uptake value of 2-[18 F]fluoro-2-deoxy-Dglucose. Int J Radiat Oncol Biol Phys 59, 1295–300. , et al. (2003) Radiation treatment planning with an integrated positron emission and computer tomography (PET/CT): a feasibility study. Int J Radiat Oncol Biol Phys 57, 853–63. W. (2005) Comparison of CT- and FDG-PET-defined gross tumor volume in intensity-modulated radiotherapy for head-and-neck cancer. Int J Radiat Oncol Biol Phys 61, 1385–92.

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